Testosterone replacement is likely to be beneficial in healthy older individuals with significant hypogonadism. Testosterone replacement in people with borderline syndrome. Testosterone replacement in people with testosterone levels bordering on low or low levels of normal has not yet proven effective and may not outweigh the risks. Testosterone levels naturally decrease as that you're getting old.
While testosterone therapy may be an option, it also has disadvantages. Some older people who receive testosterone therapy may be at greater heart risk. Instead, you may be interested in natural testosterone boosters. Many over-the-counter (OTC) products make claims, but there's limited research to back them up.
The substantial increase in men's life expectancy has increasingly focused attention on quality of life problems associated with reproductive aging. Serum levels of total and free testosterone in men, after peaking in the second and third decades of life, gradually decline with age. The trajectory of age-related decline is affected by comorbidities, adiposity, medications and genetic factors. Testosterone treatment in older men with low testosterone levels improves general sexual activity, sexual desire, and erectile function; improves areal and volumetric bone density, as well as estimated bone strength in the spine and hips; corrects unexplained anemia caused by aging; increases skeletal muscle mass, strength, and power, self-reported mobility, and some measures of physical function; and modestly improves depressive symptoms. The long-term effects of testosterone on major cardiovascular events and the risk of prostate cancer remain unclear.
The Endocrine Society recommends not giving testosterone therapy to all older men with low testosterone levels, but suggests considering treatment on an individual basis in men who have consistently low testosterone levels and symptoms or conditions that suggest a testosterone deficiency. If symptoms of low testosterone affect older men or their lifestyle, testosterone replacement therapy may be beneficial. There are several factors that can determine if treatment is necessary, and older people can talk to their healthcare providers.