No interactions were found between testosterone and Zoloft. However, this doesn't necessarily mean that there aren't any interactions. Always consult your healthcare provider to ensure that the information shown on this page applies to your personal circumstances. Research is still new, but antidepressant medications may lower testosterone in some people.
However, this side effect is treatable and is usually mild. Yes, antidepressants and hormone replacement therapy can be taken safely at the same time; many people take this combination of medications. Your doctor will advise you on the best combination of medications for you. Lifestyle strategies, such as making dietary changes or incorporating certain vitamin or mineral supplements, can sometimes help increase low testosterone levels. However, if your testosterone levels are abnormally low, your doctor may prescribe testosterone replacement therapy to help your levels rise again quickly.
For example, antidepressants appeared to lower testosterone levels in some studies, but to increase hormone levels in others. Testosterone is a hormone that stimulates sperm production and sexual desire, and helps build muscle and bone mass. According to the researchers, while antidepressants seem to influence testosterone and estrogen levels, the results of the studies are mixed. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men.
If they determine that your testosterone levels are low, they may offer you lifestyle suggestions or prescribe medications to help bring your levels back to normal. Understanding how low testosterone levels can affect you can make it easier to communicate with your partner. Because testosterone plays such an important role in the human body, low testosterone levels can cause a wide range of symptoms. Therefore, while there seems to be a relationship between antidepressants and changes in testosterone levels, more research is needed to determine the extent of this relationship. Learn about testosterone boosters or supplements that aim to promote testosterone production and what they can do to reduce libido.
Not only is testosterone the primary puberty hormone in men, but it also plays a role in sexual desire, bone health, muscle formation, red blood cell production, and more. While research is limited, low doses of testosterone may be useful for post-menopausal care, decreased libido, and gender-affirming care and more. Of the six SSRIs tested, all decreased testosterone levels and increased the estrogen to testosterone ratio. If antidepressants are the cause of low testosterone, you may also decide that you want to change medications or stop taking them completely.
