Testosterone has a range of effects on the male body. This review attempts to determine, based on published studies, the temporal evolution of the effects induced by testosterone replacement therapy from its first manifestation until maximum effects are reached. It should be noted that almost none of the studies cited were specifically designed to evaluate the temporal evolution of the effects. Some studies measure the effects of testosterone only after 3 months (3) and, in particular, the effects on libido and erections have occurred long before this time period (14, 6).
We have observed significant differences in the occurrence of the effects of testosterone. The effects on libido and other psychological variables and the effects on the vasculature occur quite rapidly. It is quite possible that these effects are not mediated by the classic androgen receptor, but by other mechanisms, such as effects on membranes (6,. In addition, the effects on erection occur quite rapidly and can be explained in part by non-genomic effects on the vascular erectile tissue of the penis (8).
Soon after starting hormone treatment, you may notice a change in your libido. Quite quickly, your genitals, especially the clitoris, will start to grow and get even bigger when you're aroused. You may find that different sexual acts or different parts of your body bring you erotic pleasure. Your orgasms will feel different, perhaps with a higher maximum intensity and a greater focus on the genitals rather than on a full-body experience.
Some people find that their sexual interests, attractions, or orientation can change when they take testosterone; it's better to explore these new feelings rather than keep them suppressed. Many people are happier after nine months of testosterone therapy because they can see the physical changes in their body. Although body odor may become even more intense at this point and sweating may not yet be under control, it's at this point that you'll finally have the look you've always wanted. The hair on the sideburns, eyebrows and chin will thicken even more, and some people may even grow a beard after 12 months of testosterone treatment. In addition, the Adam's apple should be prominent at this stage.
If menstrual bleeding doesn't stop after taking testosterone for several months, your healthcare professional may recommend that you take medication to stop it. If you're considering hormone replacement therapy or are starting to use it for the first time, it's important to know what effects to expect and when to expect them. Keep in mind that everyone is different and that not everyone will follow the same path. These deadlines are rough estimates that give you an idea of how the transition could progress. Here, we explore the timeline of FTM testosterone changes and the timeline of the MTF HRT effect. Often, people who seek to maintain certain changes will take testosterone therapy for the rest of their lives.
However, not all trans men will experience a total deepening of the tone of their voice with testosterone. Some of the physical changes caused by masculinizing hormone therapy can be reversed if you stop taking testosterone. The search was limited to tests conducted with testosterone, including testosterone esters and dihydrotestosterone preparations, regardless of childbirth. Notably, the effects were more pronounced in men with the lowest baseline testosterone levels (7).
Once you've reached male testosterone levels, taking higher doses won't cause faster or more dramatic changes, but it can cause more side effects or complications. Testosterone will cause the vocal cords to thicken, making the voice sound more masculine. A person who isn't binary or androgynous might want to take a lower dose of testosterone to achieve higher testosterone levels than they naturally have, but not so high as to be within the average range for a cisgender man, he says. Transgender men can become pregnant while taking testosterone, so if you have sex with someone who is capable of producing sperm, you should always use birth control to avoid a unwanted pregnancy.
Excess testosterone can cause mood symptoms or irritability, bloating, pelvic cramps, or even the return of menstruation. In a larger group of men with severe depression (n = 2 × 50), effects of testosterone replacement therapy (TRT) with gel compared to placebo were seen within 6 weeks. Other forms of testosterone that may be suitable for some people include placing testosterone pellets under the skin, a long-acting injection, and the administration of an oral capsule twice daily. These platforms also offer the option of connecting virtually with a health professional that includes trans people, so you can ask your personal questions and determine if testosterone therapy is right for you.
If patients have not been exposed to testosterone at the usual time of puberty, they should be prepared and counseled about the onset of sexual thoughts and dreams, the increase in erections and seminal emissions, and when to expect them. That said, surgeons usually recommend waiting at least 6 to 12 months after starting testosterone therapy before undergoing masculinizing chest surgery, also known as upper surgery, to first allow the contours of the muscles and soft tissues of the chest wall to adapt to their new pattern. Insulin sensitivity may improve within a few days, but effects on glycemic control become apparent only after 3 to 12 months. While most people who take testosterone notice an improvement in their mood, others notice that it may have little effect optimistic.
