You can continue testosterone replacement therapy as long as it benefits your symptoms and doesn't cause health problems. The TRT is designed to be long-term. You can continue testosterone replacement therapy as long as it benefits your symptoms and doesn't cause health problems. TRT is intended to be a long-term therapy.
If you stop taking testosterone, your levels will return to baseline. Testosterone has a range of effects on the male body. This review attempts to determine, based on published studies, the temporal evolution of the effects induced by testosterone replacement therapy from its first manifestation until maximum effects are reached. It should be noted that almost none of the studies cited were specifically designed to evaluate the temporal evolution of effects.
Some studies measure the effects of testosterone only after 3 months (3) and, in particular, the effects on libido and erections have occurred long before this time period (14, 6). We noticed significant differences in the onset of the effects of testosterone. The effects on libido and other psychological variables and the effects on the vasculature occur quite rapidly. It is quite possible that these effects are not mediated by the classic androgen receptor, but by other mechanisms, such as effects on membranes (6,.
In addition, the effects on erection occur quite rapidly and can be explained in part by non-genomic effects on the vascular erectile tissue of the penis (8). TRT doesn't cure low testosterone levels), so symptoms may come back if you stop to take it. Are you considering testosterone therapy to help you feel younger and stronger as you age? Know the risks before making a decision. A relatively small number of men experience the immediate side effects of testosterone supplementation, such as acne, breathing disorders while sleeping (worsening of sleep apnea), breast swelling or tenderness, or swelling in the ankles.
Doctors also monitor high red blood cell counts, which may increase the risk of blood clots. Men who are no longer interested in conceiving may benefit from safe and monitored testosterone replacement therapy. Some patients with genetic problems that cause subfertility, such as Klinefelter syndrome, may also benefit. High levels of these hormones normally cause the testicles to produce more testosterone and sperm.
Testosterone treatment has also been reported to improve hemoglobin concentrations, which also appears to improve anemia regardless of etiology. It's also possible that these conditions cause low testosterone levels, so treatment may cause increased testosterone levels. Many men and a surprising number of providers don't realize that taking exogenous (synthetic) testosterone or over-the-counter supplements can have harmful side effects if not properly administered. Meanwhile, comorbidities, such as obesity and diabetes mellitus, were relatively high in clinical trials of testosterone.
In general, due to the current lack of long-term safety studies on testosterone therapy, testosterone replacement therapy in older men should be used with caution. The FDA does not approve the use of TRT in men with low testosterone levels without an associated medical condition. The long-term efficacy of testosterone treatment (more than 2 years) is questionable based on the few controlled studies of long-term treatment. Serum testosterone levels gradually decline with age at a rate of approximately 1% per year after the third decade of life.
Whether this is a true form of hypogonadism or a decrease in serum testosterone associated with the progressive accumulation of health problems with aging (95, 9) is still hotly debated, but rather regardless of the aging process itself. Testosterone replacement is likely to be beneficial in healthy older people with significant hypogonadism. Primary hypogonadism occurs when something is wrong with the testicles and doesn't allow them to produce normal levels of testosterone.
