How Long Does It Take for Testosterone Replacement Therapy to Start Working?

Testosterone replacement therapy (TRT) is a popular treatment option for men with low testosterone levels. Healthcare providers often prescribe TRT to supplement men's natural production of this vital sex hormone.

How Long Does It Take for Testosterone Replacement Therapy to Start Working?

When you hear about the benefits of testosterone therapy (an accelerated sex drive, more energy, and a way to finally get rid of that stubborn instinct), it's easy to understand why so many men are trying it. We look for key indicators such as free testosterone, DHEA, vitamin D and SHBG to understand how the body uses testosterone. Men diagnosed with low testosterone levels, often called “low T”, experience symptoms that range from lack of energy and productivity, reduced sexual desire, depression, and mental confusion. Testosterone replacement therapy (TRT) is a popular treatment option for men with low testosterone levels, and TRT Fresno is one of the leading providers of this service in the area. Healthcare providers often prescribe TRT to supplement men's natural production of this vital sex hormone.

Rejuvime Medical is a wellness and anti-aging clinic that offers bioidentical hormone replacement therapy and other services at its 3 centers in Baton Rouge, Metairie, Slidell and Shreveport, Louisiana. Creams, patches, and gels may be effective, but the results will take longer to appear than with testosterone injections. In 1990, Congress passed a law that regulated anabolic steroids, including TRT, as controlled substances in the United States. Many people who start TRT wonder how long it will take for their treatment to start working.

On average, I expect people to feel some improvement in about three weeks. For some, it may take longer - three to six months. If you start to feel better early on, you may not receive all the benefits for several months. The effects on quality of life occur within 3 to 4 weeks, but the maximum benefits take longer.

The effects on depressed mood become detectable after 3 to 6 weeks, with a maximum after 18 to 30 weeks. The effects on erythropoiesis are evident after 3 months and peak at 9 to 12 months. TRT may begin to help improve sexual desire and sexual performance within 3 to 4 weeks, and maximum benefits usually stabilize after six weeks. While you may notice an improvement in as little as three weeks, it can take up to six months before you see the full benefits of TRT in erectile dysfunction.

Improvements in insulin sensitivity levels can be seen one week after undergoing testosterone replacement therapy. Decreases in triglycerides can be seen after 4 weeks and 3 months, extending to 12 months. Researchers have also observed that total cholesterol levels decrease between 4 weeks and 3 months. Testosterone administration may improve inflammatory markers, including C-reactive protein (CRP) within three weeks.

These hormone injections work the same way as testosterone produced naturally by the body would and have been shown to be clinically effective. Testosterone injections won't start working overnight, and some symptoms of low testosterone take longer to improve than others. One study administered 200 mg of testosterone enanthate every 2 weeks for 36 months to men with low testosterone levels.

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